Glossary and learn more
Short definitions of the words used on this site, plus where to read more.
Glossary
- Amino acid
- One of the 20 standard building blocks that are joined in a chain to make a protein.
- Protein
- A large molecule made of a folded chain of amino acids that does a job in a cell.
- Sequence
- The order of amino acids in a protein chain.
- Folding
- The process by which a protein chain curls into its working 3D shape.
- Structure
- The 3D arrangement of a molecule's atoms.
- Binding affinity
- How strongly one molecule, such as a drug candidate, sticks to another, such as a protein.
- Ligand
- A small molecule that binds to a protein.
- Diffusion model
- A type of AI that builds an output by gradually removing noise, step by step.
- Protein Data Bank
- A public archive of experimentally determined molecular structures.
- AlphaFold
- A series of AI systems from DeepMind that predict protein structures.
- Open source
- Software whose code is shared so that anyone can read, use and build on it.
- CSAIL
- The Computer Science and Artificial Intelligence Laboratory at MIT.
Learn more
This site is an independent summary. For authoritative details, search for these official sources:
- The Boltz project on GitHub (search for "jwohlwend/boltz").
- The Boltz-1 and Boltz-2 papers, posted on bioRxiv by the MIT authors.
- The Protein Data Bank (rcsb.org).